منابع مشابه
Polymorphism and Genetic Diversity of BAT25 Marker in Colorectal Cancer
By its frequency, colorectal cancer (CRC) has become a serious public health problem. BAT25 marker is included in the panel of five markers dedicated to the diagnosis of CCR microsatellite instability. The objective of this study was to evaluate the polymorphism and genetic diversity of the BAT25 marker in CRC cases in Senegal. This prospective study was performed on 22 CRC patients. After DNA ...
متن کاملGenetic instability in colorectal cancer.
The development of neoplasia has been thought to be associated with genetic alterations for many years. In colorectal cancer two specific types of genetic instability have been defined. One is associated with chromosomal instability and the other with DNA microsatellite instability, also known as replication errors. The mechanism underlying tumorigenesis leads to profound diVerences in the path...
متن کاملGenetic instability in colorectal cancer
The development of neoplasia has been thought to be associated with genetic alterations for many years. In colorectal cancer two specific types of genetic instability have been defined. One is associated with chromosomal instability and the other with DNA microsatellite instability, also known as replication errors. The mechanism underlying tumorigenesis leads to profound diVerences in the path...
متن کاملGenetic instability in colorectal cancer
The development of neoplasia has been thought to be associated with genetic alterations for many years. In colorectal cancer two specific types of genetic instability have been defined. One is associated with chromosomal instability and the other with DNA microsatellite instability, also known as replication errors. The mechanism underlying tumorigenesis leads to profound diVerences in the path...
متن کاملRole of Molecular Biomarkers in Colorectal Cancer
Colorectal cancer (CRC) is amongst the most widespread cancers and is a most common cause of cancer associated mortality universally. Since previous decades, it has been cleared that CRC develops owing to the buildup of a series of genetic and epigenetic changes in the normal colonic epithelium. Regardless of the current development in surgery and therapies, overall survival of end stage CRC pa...
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ژورنال
عنوان ژورنال: Gut
سال: 2015
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2013-306705